Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CCNH | P51946 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.30 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943071 | 0.77 | KDM4E (0.30) | KDM4ESMN1; SMN2 | |
| SCHEMBL10550622 | 0.74 | ALDH1A1 (0.39) | KDM4EALDH1A1POLA1RXFP1CDK2 | |
| SCHEMBL31058752 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1POLA1RXFP1CDK2 | |
| SCHEMBL3578267 | 0.73 | ALDH1A1 (0.53) | KDM4EALDH1A1POLA1RXFP1CDK2 | |
| SCHEMBL16178779 | 0.70 | ALDH1A1 (0.46) | KDM4EALDH1A1POLA1RXFP1CDK2 | |
| 2-Aminopurine SCHEMBL4342854 | 0.69 | ALDH1A1 (0.79) | KDM4EALDH1A1POLA1RXFP1CDK2 | |
| SCHEMBL5033486 | 0.68 | CDK2 (0.49) | KDM4EALDH1A1RXFP1CDK2PAK1 | |
| SCHEMBL11077322 | 0.67 | ALDH1A1 (0.50) | KDM4EALDH1A1POLA1RXFP1CDK2 | |
| SCHEMBL375956 | 0.67 | ALDH1A1 (0.59) | KDM4EALDH1A1POLA1RXFP1CDK2 | |
| SCHEMBL5138814 | 0.66 | ALDH1A1 (0.53) | KDM4EALDH1A1POLA1RXFP1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131323-A1 | SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES | Medivir Aktiebolag (SE) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000008025-A1 | SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES | MEDIVIR AB (SE) | 2000-02-17 | — | — | WO | disclosed |