Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950137 | 0.83 | MEN1 (0.40) | MEN1ALDH1A1KMT2ANOTUMPIM1 | |
| SCHEMBL8093004 | 0.79 | ALOX5 (0.37) | MEN1ALDH1A1MAPTKMT2ANOTUM | |
| SCHEMBL8101846 | 0.78 | ALOX5 (0.35) | MEN1ALDH1A1MAPTKMT2ANOTUM | |
| SCHEMBL24194641 | 0.76 | NOTUM (0.53) | IDH2NOTUMPIM1 | |
| SCHEMBL24742649 | 0.74 | LMNA (0.44) | MEN1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL22813701 | 0.71 | HTR2C (0.42) | IDH2ALDH1A1MAPTNOTUM | |
| SCHEMBL4661338 | 0.67 | TSHR (0.54) | ALDH1A1MAPT | |
| SCHEMBL1410138 | 0.67 | NOTUM (0.67) | IDH2ALDH1A1MAPTNOTUMPOLB | |
| SCHEMBL13040490 | 0.67 | TSHR (0.45) | IDH2ALDH1A1L3MBTL1 | |
| SCHEMBL20048770 | 0.67 | TSHR (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |