Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943305 | 0.83 | IDH2 (0.44) | MEN1KMT2APIM1PIM2DRD2 | |
| SCHEMBL8093004 | 0.76 | ALOX5 (0.37) | MEN1KMT2ANOTUMALDH1A1 | |
| SCHEMBL7950089 | 0.74 | CARM1 (0.39) | CARM1PRMT6ALDH1A1BACE1SLC6A4 | |
| SCHEMBL7945321 | 0.74 | CARM1 (0.39) | CARM1PRMT6ALDH1A1BACE1SLC6A4 | |
| SCHEMBL8101846 | 0.73 | ALOX5 (0.35) | MEN1KMT2ANOTUMALDH1A1 | |
| SCHEMBL31587536 | 0.71 | L3MBTL1 (0.46) | MEN1KMT2APIM1CARM1PRMT6 | |
| SCHEMBL24194641 | 0.70 | NOTUM (0.53) | PIM1NOTUM | |
| SCHEMBL7951897 | 0.69 | KMT2A (0.61) | MEN1KMT2ATP53 | |
| SCHEMBL22813701 | 0.68 | HTR2C (0.42) | NOTUMALDH1A1 | |
| SCHEMBL7944872 | 0.68 | KMT2A (0.51) | MEN1KMT2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |