Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101846 | 0.82 | ALOX5 (0.35) | ALOX5ALDH1A1HTR3EHTR3BHTR1D | |
| SCHEMBL7943305 | 0.79 | IDH2 (0.44) | ALDH1A1MAPTLMNAPOLBHPGD | |
| SCHEMBL7950137 | 0.76 | MEN1 (0.40) | ALDH1A1NOTUMMEN1KMT2A | |
| SCHEMBL24194641 | 0.71 | NOTUM (0.53) | NOTUM | |
| SCHEMBL4661338 | 0.68 | TSHR (0.54) | ALDH1A1HTR3EHTR3BHTR2CHTR3A | |
| SCHEMBL13040490 | 0.68 | TSHR (0.45) | ALDH1A1HTR3EHTR3BHTR2CHTR3A | |
| SCHEMBL20048770 | 0.68 | TSHR (0.50) | ALDH1A1HTR3EHTR3BHTR2CHTR3A | |
| SCHEMBL22813701 | 0.67 | HTR2C (0.42) | ALDH1A1HTR3EHTR3BHTR1DHTR2C | |
| SCHEMBL16139507 | 0.65 | TSHR (0.42) | ALDH1A1HTR3EHTR3BHTR2CHTR3A | |
| SCHEMBL1847671 | 0.64 | ALDH1A1 (0.41) | ALOX5ALDH1A1SIGMAR1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008150447-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2008-12-11 | — | — | WO | disclosed |