Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | MMP9 | P14780 | 2/20 | 0.59 |
| ▸ | MMP8 | P22894 | 2/20 | 0.59 |
| ▸ | MMP13 | P45452 | 2/20 | 0.59 |
| ▸ | CHEK2 | O96017 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.53 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.53 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.53 |
| ▸ | MPL | P40238 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564579 | 0.91 | CHEK2 (0.61) | KDM4EALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL7943528 | 0.89 | MMP2 (0.71) | KDM4EALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL11599478 | 0.88 | KDM4E (0.70) | KDM4EALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL7602620 | 0.88 | KDM4E (0.70) | KDM4EALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL3564386 | 0.88 | CHEK2 (0.64) | KDM4EALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL28930292 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL14494924 | 0.86 | NPC1 (0.60) | KDM4EALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL7036871 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL7444528 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1HPGDKMT2AMMP2 | |
| SCHEMBL7574964 | 0.85 | NPC1 (0.58) | KDM4EALDH1A1HPGDKMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251689-B1 | BINDING TO RESIN; OXIDATION | TELIK, INC. | 2001-06-26 | — | — | US | claimed |