Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616776 | 0.83 | TAAR1 (0.67) | ADRA2AMAPK1HIF1AKDM4EMAPT | |
| SCHEMBL3577593 | 0.82 | ABAT (0.46) | ABATENPP2ADRA2AMAPK1HIF1A | |
| SCHEMBL17058723 | 0.81 | CA1 (0.61) | ADRA2AMAPK1HIF1AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5318190 | 0.81 | MAPK1 (0.68) | ADRA2AMAPK1HIF1AKDM4EMAPT | |
| SCHEMBL7942390 | 0.79 | KDM4E (0.41) | ADRA2AMAPK1HIF1AKDM4EMAPT | |
| SCHEMBL29875484 | 0.78 | LOXL2 (0.46) | ABATENPP2TAAR1GAAHRH3 | |
| SCHEMBL28879957 | 0.78 | LOXL2 (0.46) | ABATENPP2TAAR1GAAHRH3 | |
| SCHEMBL110644 | 0.78 | KDM4E (0.67) | ABATADRA2AMAPK1HIF1AKDM4E | |
| SCHEMBL29359577 | 0.78 | KDM4E (0.67) | ABATADRA2AMAPK1HIF1AKDM4E | |
| SCHEMBL6104943 | 0.77 | THRB (0.40) | ADRA2AMAPK1HIF1AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054278-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |