Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | DRD1 | P21728 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 2/20 | 0.67 |
| ▸ | DRD5 | P21918 | 2/20 | 0.67 |
| ▸ | DRD3 | P35462 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HTR1A | P08908 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5318190 | 0.98 | MAPK1 (0.68) | TAAR1MAPK1KDM4EADRA2ASLC6A2 | |
| SCHEMBL14575050 | 0.83 | TAAR1 (0.67) | TAAR1MAPK1KDM4EADRA2ASLC6A2 | |
| SCHEMBL13886597 | 0.83 | TAAR1 (0.74) | TAAR1MAPK1KDM4EADRA2ASLC6A2 | |
| SCHEMBL7943754 | 0.83 | ABAT (0.46) | TAAR1MAPK1KDM4EADRA2ASLC6A2 | |
| SCHEMBL5212328 | 0.81 | KDM4E (0.65) | TAAR1MAPK1KDM4EADRA2ASLC6A2 | |
| SCHEMBL13886595 | 0.81 | TAAR1 (0.56) | TAAR1MAPK1KDM4EADRA2ASLC6A2 | |
| Dopamine SCHEMBL496657 | 0.80 | KDM4E (1.00) | TAAR1MAPK1KDM4EADRA2ASLC6A2 | |
| Dopamine SCHEMBL18159501 | 0.80 | KDM4E (1.00) | TAAR1MAPK1KDM4EADRA2ASLC6A2 | |
| Dopamine SCHEMBL8505 | 0.80 | KDM4E (1.00) | TAAR1MAPK1KDM4EADRA2ASLC6A2 | |
| Dopamine SCHEMBL9166387 | 0.80 | KDM4E (1.00) | TAAR1MAPK1KDM4EADRA2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3930948-A | ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES | AJINOMOTO CO., INC. (JA) | 1976-01-06 | — | — | US | claimed |
| CN-117986264-A | Benzo nitrogen-containing polycyclic derivative regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20190105409-A9 | IMAGING AGENTS WITH IMPROVED PHARMACOKINETIC PROFILES | GE HEALTHCARE AS (NO) | 2019-04-11 | — | — | US | disclosed |
| US-10220100-B2 | Halogenated phenols for diagnostics, antioxidant protection and drug delivery | LATHAM KEITH R (US) | 2019-03-05 | — | — | US | disclosed |
| US-20180369395-A9 | Halogenated Phenols for Diagnostics, Antioxidant Protection and Drug Delivery | LATHAM KEITH R (US) | 2018-12-27 | — | — | US | disclosed |
| US-20180117164-A1 | Halogenated Phenols for Diagnostics, Antioxidant Protection and Drug Delivery | LATHAM KEITH R (US) | 2018-05-03 | — | — | US | disclosed |
| US-9144613-B2 | Halogenated phenols for diagnostics, antioxidant protection and drug delivery | LATHAM KEITH R (US) | 2015-09-29 | — | — | US | disclosed |
| US-9125946-B2 | Halogenated phenols for diagnostics, antioxidant protection and drug delivery | LATHAM KEITH R (US) | 2015-09-08 | — | — | US | disclosed |
| US-20140286866-A1 | IMAGING AGENTS WITH IMPROVED PHARMACOKINETIC PROFILES | GE HEALTHCARE AS (NO) | 2014-09-25 | — | — | US | disclosed |
| EP-2755939-A2 | HALOGENATED PHENOLS FOR DIAGNOSTICS, ANTIOXIDANT PROTECTION AND DRUG DELIVERY | Latham, Keith, R. (US) | 2014-07-23 | — | — | EP | disclosed |
| EP-1682113-B1 | INHIBITOR IMAGING AGENTS | GE HEALTHCARE LTD (GB) | 2008-01-23 | — | — | EP | disclosed |
| US-20070104644-A1 | Inhibitor imaging agents | CUTHBERTSON ALAN | 2007-05-10 | — | — | US | disclosed |
| CN-1901894-A | Inhibitor imaging agents | GE HEALTHCARE LTD (GB) | 2007-01-24 | — | — | CN | disclosed |
| EP-1682113-A1 | INHIBITOR IMAGING AGENTS | GE Healthcare Limited (GB) | 2006-07-26 | — | — | EP | disclosed |
| WO-2006004429-A2 | IMAGING AGENTS COMPRISING A NON- PEPTIDIC VECTOR LINKED TO A FLUOROPHORE VIA A POLYETHYLENE GLYCOL LINKER | GE HEALTHCARE AS (NO) | 2006-01-12 | — | — | WO | disclosed |
| WO-2005049005-A1 | INHIBITOR IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2005-06-02 | — | — | WO | disclosed |
| EP-0595743-B1 | Bihaptinic derivatives for binding technetium or rhenium, process for their preparation, application for diagnosis and therapy, kits and immunological reactants comprising them. | IMMUNOTECH PARTNERS (FR) | 2001-03-14 | — | — | EP | disclosed |
| EP-0595743-A1 | Bihaptinic derivatives for binding for technetium or rhenium, process for their preparation, application for diagnosis and therapy, kits and immunological reactants comprising them | IMMUNOTECH PARTNERS:Société Anonyme dite (FR) | 1994-05-04 | — | — | EP | disclosed |
| US-5242680-A | Diagnostic and therapeutic | MERCK & CO., INC. (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0524722-A1 | Thiol-reactive maleimido-based radiolabeling reagents | MERCK & CO. INC. (US) | 1993-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190105409-A9 | IMAGING AGENTS WITH IMPROVED PHARMACOKINETIC PROFILES | SLC10A1, SLC10A2, SLC19A1 | TAAR1 1265/4885MAPK1 4828/4885KDM4E 4117/4885 |
| US-20180369395-A9 | Halogenated Phenols for Diagnostics, Antioxidant Protection and Drug Delivery | COMT, GPX4, GPX1 | TAAR1 2120/4885MAPK1 3227/4885KDM4E 1845/4885 |
| US-10220100-B2 | Halogenated phenols for diagnostics, antioxidant protection and drug delivery | COMT, GPX4, GPX1 | TAAR1 2120/4885MAPK1 3227/4885KDM4E 1845/4885 |
| US-20180117164-A1 | Halogenated Phenols for Diagnostics, Antioxidant Protection and Drug Delivery | COMT, GPX4, GPX1 | TAAR1 2120/4885MAPK1 3227/4885KDM4E 1845/4885 |
| US-20140286866-A1 | IMAGING AGENTS WITH IMPROVED PHARMACOKINETIC PROFILES | SLC10A1, SLC10A2, SLC19A1 | TAAR1 1265/4885MAPK1 4828/4885KDM4E 4117/4885 |
| US-20070104644-A1 | Inhibitor imaging agents | MMP3, MMP1, MMP10 | TAAR1 3892/4885MAPK1 2045/4885KDM4E 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.