Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797241 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL7805593 | 0.79 | HTR7 (0.52) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6562176 | 0.76 | ALDH1A1 (0.54) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7805578 | 0.75 | HTR7 (0.48) | HTR7ALDH1A1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL6560069 | 0.71 | HTR7 (0.55) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7807349 | 0.69 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7946819 | 0.69 | HTR7 (0.52) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6767953 | 0.68 | HTR7 (0.45) | HTR7ALDH1A1KDM4ESMN1; SMN2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6768275 | 0.68 | HTR7 (0.44) | HTR7ALDH1A1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL29904797 | 0.67 | HTR7 (1.00) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |