Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | CALML3 | P27482 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SDHA | P31040 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368026 | 0.90 | MAOA (0.47) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL7945892 | 0.90 | MAOA (0.56) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL7938083 | 0.90 | MAOA (0.56) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL8484607 | 0.88 | MAOA (0.66) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL7949645 | 0.88 | MAOA (0.66) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL7938096 | 0.86 | MAOA (0.54) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL7945883 | 0.86 | MAOA (0.54) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL21324902 | 0.84 | ABCB11 (0.51) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL10423881 | 0.84 | ABCB11 (0.51) | MAOACYP3A4CYP2D6MAOBCALML3 | |
| SCHEMBL8339574 | 0.83 | MAOA (0.51) | MAOACYP3A4CYP2D6MAOBCALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3176626-B2 | — | — | 2001-06-18 | — | — | JP | claimed |
| US-5565571-A | BACTERICIDES | THE UPJOHN COMPANY (US) | 1996-10-15 | — | — | US | claimed |
| EP-0610265-A1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS. | UPJOHN CO (US) | 1994-08-17 | — | — | EP | claimed |
| WO-1993009103-A1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1993-05-13 | — | — | WO | claimed |
| EP-0610265-A1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS. | UPJOHN CO (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993009103-A1 | SUBSTITUTED ARYL- AND HETEROARYLPHENYLOXAZOLIDINONES USEFUL AS ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |