Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093809 | 1.00 | TSHR (0.60) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL3126651 | 0.83 | GLA (0.58) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL7944695 | 0.83 | TSHR (0.53) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL3126653 | 0.83 | GLA (0.58) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL7933394 | 0.82 | CYP11B2 (0.45) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL9190390 | 0.81 | ERN1 (0.49) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL9723906 | 0.81 | ALDH1A1 (0.54) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL9723904 | 0.81 | ALDH1A1 (0.54) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL9723882 | 0.77 | MAPT (0.49) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9723883 | 0.77 | MAPT (0.49) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242634-B1 | OF HERBICIDES, HALOPHENYL COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6100257-A | 2-HALOALKYL,3-(HALOALKYL, ALKENYL, OR ALKYNYL),5-(SUBSTITUTED PHENYL OR HETEROCYCLE),6-ALKYL-PYRIMIDIN-4-ONE COMPOUNDS OF GIVEN STRUCTURE; USE AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0850229-A1 | PYRIMIDIN-4-ONE DERIVATIVES, THEIR USE AS HERBICIDES, INTERMEDIATES FOR THEIR PRODUCTION AND PROCESSES FOR PRODUCING THESE COMPOUNDS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997006150-A1 | PYRIMIDIN-4-ONE DERIVATIVES, THEIR USE AS HERBICIDES, INTERMEDIATES FOR THEIR PRODUCTION AND PROCESSES FOR PRODUCING THESE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-20 | — | — | WO | disclosed |