Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18116188 | 0.78 | CYP4F2 (0.32) | CA1CYP4F2CYP4A11CA9 | |
| SCHEMBL14403409 | 0.78 | CYP1A2 (0.44) | ALDH1A1TSHRCYP4F2CYP4A11TDP1 | |
| SCHEMBL450807 | 0.77 | CYP4F2 (0.51) | ALDH1A1CA1CYP4F2CYP4A11CA9 | |
| SCHEMBL445031 | 0.75 | ALDH1A1 (0.58) | THRBALDH1A1TSHRCA1CA9 | |
| SCHEMBL12124127 | 0.73 | ALDH1A1 (0.36) | THRBALDH1A1TSHRPOLBAPEX1 | |
| SCHEMBL2785959 | 0.73 | THRB (0.53) | THRBALDH1A1TSHRCA1CA2 | |
| SCHEMBL7166144 | 0.73 | CA1 (0.42) | CA1CA9 | |
| SCHEMBL25674609 | 0.72 | THRB (0.42) | THRBALDH1A1TSHRCA1CA2 | |
| SCHEMBL16213961 | 0.72 | CYP4F2 (0.33) | CA1CYP4F2CYP4A11CA9 | |
| SCHEMBL208911 | 0.72 | THRB (0.52) | THRBALDH1A1TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258895-B1 | Polymers having spiro orthoester groups, process of manufacturing and using | THE PROCTER & GAMBLE COMPANY | 2001-07-10 | — | — | US | disclosed |
| EP-0575667-B1 | Process for the manufacture of polymers having spiro orthoester groups, the polymers obtained and their use | PROCTER & GAMBLE (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0575667-A1 | Process for the manufacture of polymers having spiro orthoester groups, the polymers obtained and their use | THE PROCTER & GAMBLE COMPANY (US) | 1993-12-29 | — | — | EP | disclosed |