Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 6/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.49 |
| ▸ | RELA | Q04206 | 6/20 | 0.49 |
| ▸ | JUN | P05412 | 5/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | XPO1 | O14980 | 2/20 | 0.44 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.43 |
| ▸ | ATF1 | P18846 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783276 | 0.83 | MAOB (0.51) | KDRKDM4EMAPTMEN1KMT2A | |
| SCHEMBL7785115 | 0.79 | KDR (0.51) | NFKB1NFKB2RELAJUNKDR | |
| SCHEMBL15707405 | 0.76 | SCN2A (0.43) | NFKB1NFKB2RELAJUNKDR | |
| SCHEMBL7979004 | 0.76 | MAPT (0.71) | NFKB1NFKB2RELAJUNKDR | |
| SCHEMBL15707438 | 0.73 | KIF11 (0.47) | KDRKDM4EMAPTMEN1KMT2A | |
| SCHEMBL4555022 | 0.73 | MAPT (0.67) | KDRKDM4EMAPTMEN1KMT2A | |
| SCHEMBL11009249 | 0.72 | MAPT (0.67) | KDM4EMAPTMEN1KMT2ATEK | |
| SCHEMBL18993441 | 0.72 | F2R (0.51) | KDM4EMAPTF2R | |
| SCHEMBL18027796 | 0.72 | RAB9A (0.56) | KDRKDM4EMAPTMEN1KMT2A | |
| SCHEMBL6811322 | 0.72 | TLR8 (0.68) | KDM4EMAPTMEN1KMT2AP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |