Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705832 | 0.88 | KMT2A (0.76) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL7946864 | 0.87 | ALDH1A1 (0.73) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL10611772 | 0.87 | KMT2A (0.73) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL7937594 | 0.85 | TDP1 (0.55) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL29193169 | 0.82 | LMNA (0.81) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL7948963 | 0.82 | LMNA (0.60) | KMT2ATDP1SLC6A2ALDH1A1L3MBTL1 | |
| Benzyl Benzoate SCHEMBL10973774 | 0.82 | TDP1 (0.82) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL2357688 | 0.82 | KMT2A (0.76) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL6057150 | 0.82 | ALDH1A1 (0.69) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL7946640 | 0.81 | ALDH1A1 (0.55) | KMT2AALDH1A1L3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051526-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051528-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051529-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |