Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946893 | 0.88 | ALDH1A1 (0.68) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL7943878 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL6057138 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL7948963 | 0.83 | LMNA (0.60) | ALDH1A1TSHRNR4A1MAPTRAB9A | |
| SCHEMBL6057230 | 0.81 | ALDH1A1 (0.77) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL7945291 | 0.81 | KMT2A (0.59) | ALDH1A1NR4A1MAPTRAB9AHPGD | |
| SCHEMBL7946641 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTRAB9AL3MBTL1 | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL298176 | 0.78 | TSHR (0.69) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL20530394 | 0.78 | TSHR (0.69) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL226501 | 0.77 | ALDH1A1 (0.86) | ALDH1A1TSHRMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051527-A1 | PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051526-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051529-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051528-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |