Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946641 | 0.90 | ALDH1A1 (0.58) | LMNAALDH1A1TDP1TSHRMEN1 | |
| SCHEMBL7946879 | 0.87 | ALDH1A1 (0.67) | LMNAALDH1A1TDP1TSHRHPGD | |
| SCHEMBL7946901 | 0.86 | LMNA (0.56) | LMNAALDH1A1CHRM1MEN1KMT2A | |
| SCHEMBL197459 | 0.84 | ALDH1A1 (0.70) | LMNAALDH1A1TDP1TSHRESR1 | |
| SCHEMBL7946640 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL7945291 | 0.82 | KMT2A (0.59) | LMNAALDH1A1TDP1SLC6A2MEN1 | |
| SCHEMBL2059610 | 0.81 | ALDH1A1 (0.76) | LMNAALDH1A1TDP1TSHRHPGD | |
| Hydrochloric Acid SCHEMBL11172092 | 0.79 | ALDH1A1 (0.73) | LMNAALDH1A1TDP1TSHRKMT2A | |
| 4-Chloro-Benzoic Acid SCHEMBL6852257 | 0.77 | ALDH1A1 (0.73) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL130761 | 0.77 | LMNA (1.00) | LMNAALDH1A1TDP1TSHRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051526-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051527-A1 | PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051529-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |