Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815400 | 0.87 | LMNA (0.49) | POLBSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL7945400 | 0.86 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2GPR35MAPTALDH1A1 | |
| SCHEMBL7939065 | 0.85 | NPC1 (0.48) | POLBSMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL6819653 | 0.82 | KDM4E (0.48) | POLBSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL6819683 | 0.81 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL6814354 | 0.81 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL6811016 | 0.80 | CA1 (0.42) | POLBSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL6811291 | 0.80 | ALDH1A1 (0.48) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL6816499 | 0.79 | ALDH1A1 (0.53) | POLBMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL7950460 | 0.78 | HDAC1 (0.46) | RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |