Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815400 | 0.88 | LMNA (0.49) | SMN1; SMN2POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL7950460 | 0.87 | HDAC1 (0.46) | RAB9ANPC1HDAC1HDAC3HDAC2 | |
| SCHEMBL7945322 | 0.86 | POLB (0.43) | SMN1; SMN2POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL6819683 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL7939065 | 0.84 | NPC1 (0.48) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| SCHEMBL6819653 | 0.83 | KDM4E (0.48) | SMN1; SMN2POLBKDM4EALDH1A1MEN1 | |
| SCHEMBL6815612 | 0.80 | HDAC1 (0.36) | SMN1; SMN2POLBKDM4EALDH1A1MAPT | |
| SCHEMBL6814354 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL7938992 | 0.77 | L3MBTL1 (0.44) | POLBLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL7666786 | 0.77 | RAB9A (0.46) | SMN1; SMN2POLBKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |