Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 15/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 15/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666786 | 0.87 | RAB9A (0.46) | NPC1RAB9A | |
| SCHEMBL7945400 | 0.87 | SMN1; SMN2 (0.41) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL7938992 | 0.84 | L3MBTL1 (0.44) | MAPK1NPC1RAB9A | |
| SCHEMBL6819653 | 0.84 | KDM4E (0.48) | NPC1RAB9ACA12CA9 | |
| SCHEMBL7939137 | 0.81 | GAA (0.45) | NPC1RAB9ACA12CA1CA9 | |
| SCHEMBL7945599 | 0.81 | RAB9A (0.61) | HDAC1HDAC6NPC1RAB9A | |
| SCHEMBL6819683 | 0.81 | SMN1; SMN2 (0.47) | NPC1RAB9A | |
| SCHEMBL6815612 | 0.81 | HDAC1 (0.36) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL6815733 | 0.81 | PLAU (0.48) | HDAC2HDAC6HDAC8NPC1RAB9A | |
| SCHEMBL6815400 | 0.80 | LMNA (0.49) | MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |