SCHEMBL7945933

SCHEMBL7945933

CCCCCCCCCCCCCCC(O)C(O)C1COC(=O)N1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 2/20 0.37
DAGLA Q9Y4D2 1/20 0.35
PRKCD Q05655 4/20 0.35
CYP2D6 P10635 2/20 0.35
GMNN O75496 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
THPO P40225 1/20 0.35
MTOR P42345 1/20 0.35
BLM P54132 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
CETP P11597 1/20 0.35
HTT P42858 1/20 0.35
UBE2N P61088 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7945981 0.85 PDCD4 (0.37) DAGLA
SCHEMBL12986294 0.81 PRKCD (0.37) DAGLAPRKCDCYP1A2
SCHEMBL17365168 0.72 CYP1A2 (0.36) CYP1A2
SCHEMBL18782741 0.71 CA2 (0.38) DAGLAPRKCD
SCHEMBL18782946 0.71 CA2 (0.38) DAGLAPRKCD
SCHEMBL18949015 0.70 CCR2 (0.40) DAGLAPRKCD
SCHEMBL18949074 0.70 CCR2 (0.40) DAGLAPRKCD
SCHEMBL1223005 0.70 LMNA (0.34) LMNAMAPT
SCHEMBL3863886 0.70 SPHK1 (0.47) SPHK1CYP2D6GMNNLMNAPOLB
SCHEMBL9833314 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6255332-B1 BLOCKING AGENTS; BARRIER L'OREAL (FR) 2001-07-03 US claimed
EP-0835650-B1 Use of oxazolidinon derivatives as antipenetrant agents in a cosmetic and/or dermatologic composition OREAL (FR) 1999-07-21 EP claimed
EP-0835650-A1 Use of oxazolidinon derivatives as antipenetrant agents in a cosmetic and/or dermatologic composition L'OREAL (FR) 1998-04-15 EP claimed
US-6255332-B1 BLOCKING AGENTS; BARRIER L'OREAL (FR) 2001-07-03 US disclosed
EP-0835650-B1 Use of oxazolidinon derivatives as antipenetrant agents in a cosmetic and/or dermatologic composition OREAL (FR) 1999-07-21 EP disclosed
EP-0835650-A1 Use of oxazolidinon derivatives as antipenetrant agents in a cosmetic and/or dermatologic composition L'OREAL (FR) 1998-04-15 EP disclosed