SCHEMBL7945981

SCHEMBL7945981

CCCCCCCCCCCCCCCC(O)C1COC(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD4 Q53EL6 1/20 0.37
DAGLA Q9Y4D2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7945933 0.85 SPHK1 (0.37) DAGLA
SCHEMBL12986294 0.83 PRKCD (0.37) DAGLA
SCHEMBL1223005 0.79 LMNA (0.34)
SCHEMBL18782946 0.74 CA2 (0.38) DAGLA
SCHEMBL18782741 0.74 CA2 (0.38) DAGLA
SCHEMBL18949015 0.72 CCR2 (0.40) DAGLA
SCHEMBL18949074 0.72 CCR2 (0.40) DAGLA
SCHEMBL17365168 0.71 CYP1A2 (0.36)
SCHEMBL9833314 0.71
SCHEMBL10337476 0.69 ALDH1A1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6255332-B1 BLOCKING AGENTS; BARRIER L'OREAL (FR) 2001-07-03 US claimed
EP-0835650-B1 Use of oxazolidinon derivatives as antipenetrant agents in a cosmetic and/or dermatologic composition OREAL (FR) 1999-07-21 EP claimed
EP-0835650-A1 Use of oxazolidinon derivatives as antipenetrant agents in a cosmetic and/or dermatologic composition L'OREAL (FR) 1998-04-15 EP claimed
US-6255332-B1 BLOCKING AGENTS; BARRIER L'OREAL (FR) 2001-07-03 US disclosed
EP-0835650-B1 Use of oxazolidinon derivatives as antipenetrant agents in a cosmetic and/or dermatologic composition OREAL (FR) 1999-07-21 EP disclosed
EP-0835650-A1 Use of oxazolidinon derivatives as antipenetrant agents in a cosmetic and/or dermatologic composition L'OREAL (FR) 1998-04-15 EP disclosed