Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.34 |
| ▸ | CASP1 | P29466 | 10/20 | 0.34 |
| ▸ | CASP7 | P55210 | 10/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.34 |
| ▸ | USP2 | O75604 | 9/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937747 | 0.93 | HSF1 (0.35) | HSF1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL7944574 | 0.91 | HSF1 (0.36) | HSF1ADORA1ADORA3ADORA2ALYN | |
| SCHEMBL7937752 | 0.86 | ADORA2A (0.39) | HSF1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL7944078 | 0.81 | PDE4B (0.42) | HSF1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL7937864 | 0.78 | ADORA2A (0.38) | CYP1A2CASP1CASP7HSD17B10USP2 | |
| SCHEMBL7946794 | 0.76 | ADORA1 (0.39) | HSF1ADORA1ADORA3ADORA2ALYN | |
| SCHEMBL7945987 | 0.76 | TYRO3 (0.36) | HSF1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL7944114 | 0.75 | PDE4B (0.48) | HSF1CYP1A2CYP3A4CYP2C9ADORA1 | |
| SCHEMBL7947006 | 0.72 | ALDH1A1 (0.34) | CYP1A2CASP1CASP7HSD17B10USP2 | |
| SCHEMBL7947184 | 0.70 | CYP1A2 (0.45) | CYP1A2CASP1CASP7HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |