Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955530 | 0.89 | HPGD (0.39) | HPGDGAAMAPTSMN1; SMN2CSNK1D | |
| SCHEMBL7960324 | 0.87 | PLAU (0.38) | GAACSNK1DCSNK1EALDH1A1KMT2A | |
| SCHEMBL7946357 | 0.87 | HPGD (0.38) | HPGDGAAMAPTSMN1; SMN2CSNK1D | |
| SCHEMBL7957120 | 0.87 | HPGD (0.38) | HPGDGAAMAPTSMN1; SMN2CSNK1D | |
| SCHEMBL7955033 | 0.78 | ALDH1A1 (0.43) | HPGDGAAALDH1A1KMT2ARAB9A | |
| SCHEMBL7955823 | 0.78 | MKNK1 (0.41) | HPGDGAAMAPTSMN1; SMN2CSNK1D | |
| SCHEMBL7946555 | 0.78 | PLAU (0.38) | HPGDMAPTSMN1; SMN2CSNK1DCSNK1E | |
| SCHEMBL7957167 | 0.77 | MKNK1 (0.40) | GAAMAPTCSNK1DCSNK1EALDH1A1 | |
| SCHEMBL7957179 | 0.76 | KMT2A (0.40) | HPGDGAAMAPTSMN1; SMN2CSNK1D | |
| SCHEMBL7953633 | 0.75 | PLAU (0.41) | GAACSNK1DCSNK1EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194426-B1 | CONTROLLING TUMOR NECROSIS FACTOR | RHONA-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |