Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946782 | 1.00 | MMP1 (0.36) | MMP1MMP13MMP3ECE1POLB | |
| SCHEMBL7960477 | 0.91 | MMP1 (0.38) | MMP1MMP13MMP3ECE1ADAM17 | |
| SCHEMBL7957224 | 0.91 | MMP1 (0.38) | MMP1MMP13MMP3ECE1ADAM17 | |
| SCHEMBL7960470 | 0.91 | MMP1 (0.38) | MMP1MMP13MMP3ECE1ADAM17 | |
| SCHEMBL7846148 | 0.90 | MMP1 (0.41) | MMP1MMP13MMP3POLBADAM17 | |
| SCHEMBL7846151 | 0.90 | MMP1 (0.41) | MMP1MMP13MMP3POLBADAM17 | |
| SCHEMBL7957364 | 0.90 | MMP1 (0.39) | MMP1MMP13MMP3ECE1CTSK | |
| SCHEMBL7827988 | 0.90 | MMP1 (0.39) | MMP1MMP13MMP3ECE1CTSK | |
| SCHEMBL7848201 | 0.87 | L3MBTL1 (0.36) | MMP1MMP13MMP3POLBBACE1 | |
| SCHEMBL7946539 | 0.83 | MMP1 (0.41) | MMP1MMP13ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281363-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; AUTOIMMUNE DISORDERS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |