Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668799 | 0.78 | ASAH1 (0.42) | MEN1KMT2ACYP2C19HPGDCYP3A4 | |
| SCHEMBL7805538 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2ACYP2C19HPGDCYP3A4 | |
| SCHEMBL7807349 | 0.71 | KDM4E (0.44) | MEN1KMT2ACYP2C19HPGDCYP3A4 | |
| SCHEMBL10059932 | 0.69 | ALDH1A1 (0.50) | MEN1KMT2ACYP2C19HPGDCYP3A4 | |
| SCHEMBL3696447 | 0.67 | ALDH1A1 (0.43) | MEN1KMT2ACYP2C19HPGDCYP3A4 | |
| SCHEMBL6561604 | 0.67 | KDM4A (0.48) | MEN1KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL3077834 | 0.66 | HPGD (0.50) | AKR1C3AKR1C2AKR1C1MEN1KMT2A | |
| SCHEMBL6760765 | 0.65 | KDM4E (0.41) | MEN1KMT2AHPGDALDH1A1HSD17B10 | |
| SCHEMBL28259595 | 0.63 | ESR1 (0.47) | MEN1KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL30228908 | 0.62 | ATM (0.47) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |