SCHEMBL6760765

SCHEMBL6760765

COc1cn(-c2ccccc2)c(=O)o1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
CYP1A2 P05177 1/20 0.41
BLM P54132 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTT P42858 1/20 0.39
LMNA P02545 1/20 0.39
MGLL Q99685 2/20 0.38
KMT2A Q03164 3/20 0.38
DDB1 Q16531 1/20 0.38
CRBN Q96SW2 1/20 0.38
GAA P10253 2/20 0.37
FAAH O00519 2/20 0.37
NR4A2 P43354 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 2/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6759687 0.84 L3MBTL1 (0.49) KDM4EALDH1A1HPGDLMNAMGLL
SCHEMBL6764283 0.83 MGLL (0.49) KDM4EALDH1A1HPGDCYP1A2LMNA
SCHEMBL7805538 0.74 ALDH1A1 (0.49) KDM4EALDH1A1HPGDCYP1A2HSD17B10
SCHEMBL4681001 0.71 FAAH (0.42) MGLLGAAFAAH
SCHEMBL4680991 0.71 HPGD (0.49) ALDH1A1HPGDHTTMGLLKMT2A
SCHEMBL11668799 0.70 ASAH1 (0.42) KDM4EALDH1A1HPGDCYP1A2BLM
SCHEMBL4676274 0.70 FAAH (0.51) ALDH1A1HPGDHSD17B10MGLLKMT2A
SCHEMBL4679478 0.70 FAAH (0.51) ALDH1A1HPGDHSD17B10MGLLKMT2A
SCHEMBL4450960 0.66 KDM4E (0.36) KDM4EALDH1A1HPGDCYP1A2BLM
SCHEMBL14883531 0.66 ALDH1A1 (0.59) KDM4EALDH1A1HPGDCYP1A2BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723860-B2 7a-alkoxy-4H-pyrano[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1207162-B1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES (JP) 2004-02-25 EP disclosed
US-6414160-B1 REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2002-06-13 US disclosed
EP-1207162-A1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same Ube Industries, Ltd. (JP) 2002-05-22 EP disclosed
EP-1000937-A1 PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS UBE INDUSTRIES LIMITED (JP) 2000-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same ACSL1, ACSL4, ACSL3 KDM4E 2201/4885ALDH1A1 11/4885HPGD 1274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.