SCHEMBL7947269

SCHEMBL7947269

Cc1cc(C(C)(C)C)c(-c2c(C(C)(C)C)ccc(OCC(CO)(CO)CO)c2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CA2 P00918 1/20 0.33
POLB P06746 1/20 0.33
TYR P14679 1/20 0.33
HSPA5 P11021 1/20 0.32
KCNJ5 P48544 1/20 0.32
KCNJ3 P48549 1/20 0.32
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
USP2 O75604 1/20 0.30
MRGPRX4 Q96LA9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28523010 0.79 USP2 (0.44) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL7208325 0.74 KCNJ5 (0.36) KCNJ5KCNJ3CYP2C9
SCHEMBL28760254 0.74
SCHEMBL2232697 0.74 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL6552135 0.73 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1CA2KCNJ5KCNJ3
SCHEMBL992037 0.70 TRPV1 (0.41) SMN1; SMN2ALDH1A1CA2CYP2C19MRGPRX4
SCHEMBL3106078 0.70 CYP2D6 (0.43) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL28610704 0.70 CYP2D6 (0.43) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL27919336 0.70 CYP2C19 (0.37) SMN1; SMN2ALDH1A1CA2CYP2C19MRGPRX4
SCHEMBL8962428 0.69 ALOX15 (0.34) ALDH1A1KCNJ5KCNJ3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160215124-A1 THERMOPLASTIC RESIN COMPOSITION, RESIN MOLDED ARTICLE, AND METHOD FOR MANUFACTURING THE RESIN MOLDED ARTICLE WITH PLATING LAYER MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2016-07-28 US disclosed
US-6265472-B1 BLEND CONTAINING COPPER PHTHALOCYANINE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-24 US disclosed
US-4888371-A HEAT RESISTANCE, LIGHT RESISTANCE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-12-19 US disclosed
EP-0255097-A2 Process for improving resistance to deterioration when exposed to sterilizing radiation of polyolefin resins ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-02-03 EP disclosed
EP-0143464-B1 PENTAERYTHRITOL-SPIRO-BIS-PHOSPHITE COMPOSITIONS HAVING IMPROVED HYDROLYTIC STABILITY Argus Chemical Corporation (US) 1987-07-08 EP disclosed
EP-0143464-A2 Pentaerythritol-spiro-bis-phosphite compositions having improved hydrolytic stability Argus Chemical Corporation (US) 1985-06-05 EP disclosed
US-4371647-A 2,6-Di-tertiary butyl phenyl pentaerythritol spiro bis-phosphites enhancing the stability to heat and light of synthetic resin ADEKA ARGUS CHEMICAL CO. LTD. (JP) 1983-02-01 US disclosed
EP-0038876-A1 2,6-Di-tertiary butyl phenyl pentaerythritol spiro bis-phosphites enhancing the stability to heat and light of synthetic resins, stabilizer compositions comprising phenolic antioxidants and such phosphites, and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-11-04 EP disclosed