SCHEMBL8962428

SCHEMBL8962428

Cc1ccc(C(C)(C)C)c(OCC(CO)(CO)CO)c1C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.34
ALDH1A1 P00352 1/20 0.31
KCNJ5 P48544 1/20 0.31
KCNJ3 P48549 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10487592 0.79 SMN1; SMN2 (0.33) ALOX15ALDH1A1
SCHEMBL27889673 0.78 CA2 (0.42) ALDH1A1
SCHEMBL7208325 0.78 KCNJ5 (0.36) KCNJ5KCNJ3
SCHEMBL2232697 0.73 SMN1; SMN2 (0.44) ALOX15ALDH1A1
SCHEMBL8433767 0.73 GABRA1 (0.32)
SCHEMBL5357080 0.73 RXRA (0.36) ALDH1A1
SCHEMBL28021313 0.73 SCN5A (0.38) ALDH1A1
SCHEMBL16829382 0.72 ALOX5AP (0.36) ALOX15ALDH1A1
SCHEMBL5347930 0.70 RXRA (0.38) ALOX15ALDH1A1
SCHEMBL6552135 0.70 ALDH1A1 (0.38) ALDH1A1KCNJ5KCNJ3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400487-B1 Styrene polymer molding material and process for preparing same IDEMITSU KOSAN CO (JP) 1996-02-07 EP disclosed
EP-0348829-B1 Nonwoven fabrics IDEMITSU KOSAN CO (JP) 1994-01-26 EP disclosed
US-5183871-A Syndiotactic, high melting, heat resistance IDEMITSU KOSAN CO., LTD. (JP) 1993-02-02 US disclosed
US-5156797-A Molding syndiotactic styrene polymer so that difference between absolute values of heat of fusion and crystallizing enthalpy on heating is at least 1 calorie per gram IDEMITSU KOSAN CO., LTD. (JP) 1992-10-20 US disclosed
US-5079075-A Molding a styrene based polymer; heat and chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1992-01-07 US disclosed
EP-0400487-A1 Styrene polymer molding material and process for preparing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-12-05 EP disclosed
EP-0348829-A2 Nonwoven fabrics IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-03 EP disclosed