Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 4/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28134012 | 0.80 | KCNJ5 (0.30) | KCNJ5KCNJ3 | |
| SCHEMBL8962428 | 0.78 | ALOX15 (0.34) | KCNJ5KCNJ3 | |
| SCHEMBL6552135 | 0.75 | ALDH1A1 (0.38) | KCNJ5KCNJ3KDM4E | |
| SCHEMBL28760254 | 0.74 | — | — | |
| SCHEMBL7947269 | 0.74 | SMN1; SMN2 (0.33) | KCNJ5KCNJ3CYP2C9 | |
| SCHEMBL27487407 | 0.72 | KDM4E (0.32) | KDM4E | |
| SCHEMBL28523010 | 0.72 | USP2 (0.44) | CYP2C9KDM4E | |
| SCHEMBL27918526 | 0.70 | ACHE (0.38) | KDM4E | |
| SCHEMBL16195513 | 0.69 | ALDH1A1 (0.50) | KDM4E | |
| SCHEMBL27385131 | 0.69 | HTR1B (0.49) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6612351-B1 | Reduced rolling resistance and heat build up; durability | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-09-02 | — | — | US | claimed |
| US-6612351-B1 | Reduced rolling resistance and heat build up; durability | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-09-02 | — | — | US | disclosed |