Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815737 | 0.87 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7947438 | 0.83 | KMT2A (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6811835 | 0.77 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6814533 | 0.75 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19465247 | 0.73 | MEN1 (0.70) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8714750 | 0.72 | MLYCD (0.63) | KMT2AMEN1ALDH1A1MAPTAHR | |
| SCHEMBL6812274 | 0.72 | KMT2A (0.54) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6814884 | 0.71 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6815741 | 0.71 | KMT2A (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31616406 | 0.70 | LMNA (0.61) | KMT2AMEN1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |