Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947433 | 0.83 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL6819526 | 0.78 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6811843 | 0.73 | ALDH1A1 (0.48) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL6815737 | 0.71 | ALDH1A1 (0.51) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7784293 | 0.70 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6815704 | 0.68 | KMT2A (0.50) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL8714750 | 0.68 | MLYCD (0.63) | KMT2AMEN1ALDH1A1MAPTAHR | |
| SCHEMBL6814706 | 0.67 | LMNA (0.41) | SMN1; SMN2ALDH1A1MAPTPHGDHL3MBTL1 | |
| SCHEMBL6816428 | 0.67 | LMNA (0.41) | KMT2ASMN1; SMN2ALDH1A1MAPK1MAPT | |
| SCHEMBL19465247 | 0.67 | MEN1 (0.70) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |