Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HAT1 | O14929 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945388 | 0.87 | BCAT2 (0.38) | BCAT2PARP10PLA2G10PLA2G2ASMN1; SMN2 | |
| SCHEMBL7784277 | 0.86 | HAT1 (0.46) | BCAT2SMN1; SMN2KMT2ARECQLMAPT | |
| SCHEMBL7657499 | 0.82 | EPHX2 (0.50) | KMT2ACYP2C19 | |
| SCHEMBL7569282 | 0.79 | HAT1 (0.40) | PARP10PLA2G10PLA2G2ASMN1; SMN2KMT2A | |
| SCHEMBL6816846 | 0.79 | OPRM1 (0.50) | PARP10PLA2G10PLA2G2AKMT2ATSHR | |
| SCHEMBL7644569 | 0.77 | ROCK2 (0.44) | PARP10PLA2G10PLA2G2ASMN1; SMN2KMT2A | |
| SCHEMBL6815624 | 0.76 | OPRM1 (0.51) | PLA2G10PLA2G2AKMT2AOPRD1OPRK1 | |
| SCHEMBL6811096 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2KMT2APOLBPARP1HSD17B10 | |
| SCHEMBL7567787 | 0.76 | PPARG (0.45) | SMN1; SMN2KMT2ARECQLTSHRHSD17B10 | |
| SCHEMBL7592313 | 0.75 | HDAC1 (0.39) | PARP10PLA2G10PLA2G2ARECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |