Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26062348 | 0.81 | MEN1 (0.46) | MEN1KMT2ANQO2KIF11KDM4E | |
| SCHEMBL187014 | 0.80 | NQO2 (0.61) | MEN1KMT2ANQO2KIF11KDM4E | |
| SCHEMBL7169139 | 0.79 | ALDH1A1 (0.64) | MEN1KMT2AKIF11KDM4ECYP1A2 | |
| SCHEMBL172788 | 0.76 | ESR1 (0.64) | MEN1KMT2ANQO2PTGS2TDP1 | |
| SCHEMBL863774 | 0.76 | CES2 (0.55) | MEN1KMT2ANQO2KIF11KDM4E | |
| SCHEMBL2839880 | 0.76 | PDE2A (0.50) | MEN1KMT2ANQO2KIF11KDM4E | |
| SCHEMBL23974528 | 0.74 | MEN1 (0.48) | MEN1KMT2ANQO2KIF11KDM4E | |
| SCHEMBL1290586 | 0.74 | ALOX15 (0.55) | MEN1KMT2ANQO2KIF11KDM4E | |
| SCHEMBL225921 | 0.74 | PDE2A (0.53) | MEN1KMT2ANQO2KIF11KDM4E | |
| SCHEMBL365939 | 0.74 | MEN1 (0.48) | MEN1KMT2ANQO2KIF11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370219-A1 | 4-Trifluor methyl mercaptophenols and their preparation | BAYER AG (DE) | 1990-05-30 | — | — | EP | claimed |
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |
| US-5382686-A | Process for preparing nitrodiphenyl (thio) ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-17 | — | — | US | disclosed |
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| EP-0304725-B1 | PROCESS FOR THE PREPARATION OF NITRO-DIPHENYL(THIO) ETHERS | BAYER AG (DE) | 1992-01-22 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0370219-A1 | 4-Trifluor methyl mercaptophenols and their preparation | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |
| EP-0370219-A1 | 4-Trifluor methyl mercaptophenols and their preparation | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |
| EP-0370219-A1 | 4-Trifluor methyl mercaptophenols and their preparation | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |
| EP-0368008-A1 | Fluorine-containing phenols | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |
| EP-0365915-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |