Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947568 | 0.81 | MEN1 (0.50) | MEN1KMT2AKIF11KDM4ENQO2 | |
| SCHEMBL187014 | 0.80 | NQO2 (0.61) | MEN1KMT2AKIF11KDM4ENQO2 | |
| SCHEMBL6519018 | 0.79 | TSHR (0.43) | ALDH1A1TSHRHPGDHSD17B10ALOX15 | |
| SCHEMBL6520621 | 0.77 | TSHR (0.41) | ALDH1A1TSHRHPGDHSD17B10ALOX15 | |
| SCHEMBL6516444 | 0.77 | TSHR (0.41) | ALDH1A1TSHRHPGDHSD17B10ALOX15 | |
| SCHEMBL6520615 | 0.77 | TSHR (0.41) | ALDH1A1TSHRHPGDHSD17B10ALOX15 | |
| SCHEMBL2001354 | 0.76 | CES2 (0.55) | MEN1KMT2AKIF11KDM4ENQO2 | |
| SCHEMBL104056 | 0.76 | CA3 (0.52) | MEN1KMT2AKIF11KDM4ENQO2 | |
| SCHEMBL226137 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2AKIF11KDM4ENQO2 | |
| SCHEMBL8985702 | 0.74 | HSD17B2 (0.49) | MEN1KMT2AKIF11KDM4ENQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159148-A2 | INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |