Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947917 | 0.91 | PDE4B (0.51) | PDE4BMAPK14ADORA3ADORA2AADORA2B | |
| SCHEMBL7946067 | 0.89 | PDE4B (0.57) | PDE4BMAPK14ADORA2AADORA2BADORA1 | |
| SCHEMBL7944713 | 0.88 | CYP1A2 (0.47) | PDE4BCFTR | |
| SCHEMBL7938164 | 0.87 | PDE4B (0.42) | PDE4BMAPK14SRCPIK3CDABL1 | |
| SCHEMBL7945984 | 0.86 | CYP1A2 (0.51) | PDE4B | |
| SCHEMBL7944647 | 0.82 | MTOR (0.53) | PDE4BMAPK14ADORA3SRCPIK3CD | |
| SCHEMBL7938416 | 0.79 | CYP1A2 (0.50) | PDE4BCFTRTLR8 | |
| SCHEMBL7946753 | 0.77 | ALDH1A1 (0.52) | — | |
| SCHEMBL7945959 | 0.75 | PDE4B (0.51) | PDE4B | |
| SCHEMBL3226765 | 0.72 | CYP1A2 (0.46) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |