Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302039 | 1.00 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL11623313 | 1.00 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7950973 | 1.00 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7563843 | 1.00 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL11626606 | 1.00 | KMT2A (0.48) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL2304429 | 0.98 | KMT2A (0.45) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL7714477 | 0.92 | CES1 (0.41) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL17673047 | 0.90 | TSHR (0.45) | KMT2AMAPTHAO1TSHRALDH1A1 | |
| SCHEMBL7951205 | 0.85 | ALDH1A1 (0.53) | KMT2AMAPTTSHRALDH1A1DGKA | |
| SCHEMBL10049892 | 0.85 | GPR84 (0.40) | KMT2AMAPTGPR84TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265440-B1 | STOMACH ULCERS | R-TECH UENO, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-5886034-A | ANTIULCER AGENTS | KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5428062-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5401768-A | Prostaglandin derivative, antiulcer, hypotensive, anticoagulant | TORAY INDUSTRIES, INC. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5380709-A | Prostaglandins E and anti ulcers containing same | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5284858-A | Prostaglandins E and anti ulcers containing same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1994-02-08 | — | — | US | disclosed |
| EP-0365678-B1 | 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF | TORAY INDUSTRIES (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5225439-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-07-06 | — | — | US | disclosed |
| US-5166174-A | For duodenal ulcers or gastric ulcers | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0284180-B1 | PROSTAGLANDINS E AND ANTI ULCERS CONTAINING SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-4113873-A | 8-AZAPROSTANOIC ACID DERIVATIVES | TANABE SEIYAKU CO. LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
| US-4079145-A | PROSTAGLANDIN ANALOGUES; SPASMOLYTIC, HYPOTENSIVE, ANTISECRETORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |
| US-4041064-A | PROSTAGLANDINS; ANTISPASMODICS, ISOTONICS, ANTIASTHMATICS, ANTIULCER AND ANTISECRETORY AGENTS | CARLO-ERBA S.P.A. (IT) | 1977-08-09 | — | — | US | disclosed |
| US-4035414-A | Prostanoic acid derivatives | CARLO ERBA S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |
| US-4035392-A | Prostanoic acid intermediate | CARLO ERBA S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |
| US-4021477-A | 14-Chloro prostadienoic acid compounds | CARLO-ERBA S.P.A. (IT) | 1977-05-03 | — | — | US | disclosed |
| US-3987072-A | CIS-4,5-Didehydro-15- or 16-alkylated 11-deoxy-PGE1 analogs | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3970684-A | Polyunsaturated prostaglandin derivatives | SYNTEX (U.S.A.) INC. (US) | 1976-07-20 | — | — | US | disclosed |
| US-3935254-A | 5C-PROSTEN-13-YNOIC ACIDS | CARLO ERBA S.P.A. (IT) | 1976-01-27 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |