Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950550 | 0.81 | CA1 (0.41) | L3MBTL1LMNAKMT2ASMN1; SMN2CA1 | |
| SCHEMBL9734583 | 0.78 | L3MBTL1 (0.49) | TDP1L3MBTL1KDM4ELMNAALOX15 | |
| SCHEMBL14578016 | 0.77 | CA12 (0.39) | L3MBTL1TSHRKMT2APOLBSMN1; SMN2 | |
| SCHEMBL5850824 | 0.76 | TDP1 (0.58) | TDP1EYA2APPACEBLM | |
| SCHEMBL5850408 | 0.76 | TDP1 (0.58) | TDP1EYA2APPACEBLM | |
| SCHEMBL2164568 | 0.76 | TDP1 (0.58) | TDP1EYA2APPACEBLM | |
| SCHEMBL15107997 | 0.75 | ALOX5 (0.41) | L3MBTL1LMNACA1CA2ALOX5 | |
| SCHEMBL12191709 | 0.74 | TDP1 (0.60) | TDP1EYA2APPACEBLM | |
| SCHEMBL8913177 | 0.74 | TDP1 (0.60) | TDP1EYA2APPACEBLM | |
| SCHEMBL15741243 | 0.74 | TDP1 (0.60) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6254850-B1 | POLYCARBOXYALKYLAMINOALKANES FOR COMPLEXES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-07-03 | — | — | US | disclosed |
| US-6040432-A | Metal complexes, of DTPA derivatives suitable for use in diagnosis and therapy | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | disclosed |