Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27464792 | 0.81 | GAA (0.43) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL28188877 | 0.79 | CPB2 (0.41) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL27703943 | 0.79 | CA2 (0.40) | KMT2APOLBGAAALDH1A1HSD17B10 | |
| SCHEMBL7948027 | 0.78 | TDP1 (0.40) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL25338592 | 0.78 | ALDH1A1 (0.40) | L3MBTL1KMT2AGAAMGAMSI | |
| SCHEMBL14578016 | 0.77 | CA12 (0.39) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL28225285 | 0.76 | ALDH1A1 (0.39) | L3MBTL1KMT2AGAAMGAMSI | |
| SCHEMBL14578018 | 0.76 | L3MBTL1 (0.38) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL22608472 | 0.74 | TP53 (0.49) | L3MBTL1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL22608474 | 0.74 | TP53 (0.49) | L3MBTL1KMT2APOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167963-A | Antitumor agents | SRI INTERNATIONAL (US) | 1992-12-01 | — | — | US | disclosed |
| EP-0388456-A1 | 8,10-DIDEAZATETRAHYDROFOLIC ACID DERIVATIVES | SRI INTERNATIONAL (US) | 1990-09-26 | — | — | EP | disclosed |
| WO-1990002745-A1 | 8,10-DIDEAZATETRAHYDROFOLIC ACID DERIVATIVES | SRI INTERNATIONAL (US) | 1990-03-22 | — | — | WO | disclosed |