Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.38 |
| ▸ | MET | P08581 | 5/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | FABP1 | P07148 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215958 | 0.88 | HTR6 (0.47) | HTR6MET | |
| SCHEMBL3213827 | 0.87 | HTR6 (0.49) | HTR6MET | |
| SCHEMBL3214748 | 0.86 | HSD11B1 (0.48) | HTR6 | |
| SCHEMBL3202680 | 0.86 | HTR6 (0.43) | HTR6METPRKCQ | |
| SCHEMBL3795831 | 0.85 | MET (0.39) | HTR6METPRKCQHTR1ADRD2 | |
| SCHEMBL3211463 | 0.85 | KDM4E (0.41) | HTR6 | |
| SCHEMBL3211299 | 0.83 | SLC40A1 (0.43) | HTR6METPRKCQ | |
| SCHEMBL3224187 | 0.81 | IDH1 (0.37) | HTR6MET | |
| SCHEMBL3205868 | 0.79 | AKT1 (0.37) | HTR6PKM | |
| SCHEMBL3222835 | 0.78 | PTGES2 (0.41) | HTR6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024980-A1 | 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-03-04 | — | — | WO | disclosed |