Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068392 | 0.85 | FFAR1 (0.48) | LMNAHPGDRAB9AMAOBLTA4H | |
| SCHEMBL22417483 | 0.83 | MAOB (0.53) | TDP1ALDH1A1CYP3A4ATMMITF | |
| SCHEMBL13302607 | 0.82 | TDP1 (0.64) | TDP1ALDH1A1LMNAALOX12TSHR | |
| SCHEMBL5297419 | 0.82 | PTGS1 (0.56) | ALDH1A1LMNANPY5RHTTMITF | |
| SCHEMBL631776 | 0.81 | KCNH3 (0.64) | TDP1ALDH1A1LMNATSHRTHRB | |
| SCHEMBL17204352 | 0.80 | KCNH3 (0.71) | TSHRPOLBKCNH3 | |
| Hydrochloric Acid SCHEMBL2249099 | 0.79 | KCNH3 (0.67) | TDP1ALDH1A1LMNATSHRTHRB | |
| SCHEMBL11420472 | 0.79 | TDP1 (0.48) | TDP1ALDH1A1LMNAALOX12TSHR | |
| SCHEMBL8310971 | 0.79 | TSHR (0.52) | ALDH1A1LMNATSHRNPY5RHTT | |
| SCHEMBL11044521 | 0.78 | ALDH1A1 (0.49) | ALDH1A1LMNANPY5RHTTMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682150-B1 | COMPOSITIONS AND METHODS FOR INDUCING CELL DEDIFFERENTIATION | SCRIPPS RESEARCH INST (US) | 2012-12-26 | — | — | EP | disclosed |
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2010039534-A2 | VIRAL AND FUNGAL INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2010-04-08 | — | — | WO | disclosed |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2009-06-04 | — | — | US | disclosed |
| US-7501404-B2 | Substituted azetidinones | DAIMED (US) | 2009-03-10 | — | — | US | disclosed |
| US-7439246-B2 | Fused heterocyclic kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-10-21 | — | — | US | disclosed |
| US-20070105832-A1 | Substituted azetidinones | Cadrenal Therapeutics, Inc. | 2007-05-10 | — | — | US | disclosed |
| US-7173031-B2 | Pyrrolotriazine kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105832-A1 | Substituted azetidinones | F2R, CPA3, CFD | TDP1 2281/4885ALDH1A1 2503/4885LMNA 1127/4885 |
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | TDP1 2281/4885ALDH1A1 2503/4885LMNA 1127/4885 |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | TDP1 2281/4885ALDH1A1 2503/4885LMNA 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.