Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 12/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946603 | 0.84 | ESR1 (0.48) | LMNATYRNR1I2ALDH1A1CYP2C9 | |
| SCHEMBL7858673 | 0.78 | ALDH1A1 (0.67) | LMNATYRNR1I2ALDH1A1CYP2C9 | |
| SCHEMBL30629387 | 0.78 | ALDH1A1 (0.67) | LMNATYRNR1I2ALDH1A1CYP2C9 | |
| SCHEMBL7948453 | 0.75 | GABRA1 (0.42) | LMNATYRNR1I2ALDH1A1CYP2C9 | |
| SCHEMBL14760222 | 0.72 | ESR1 (0.69) | ESR1ESR2AR | |
| SCHEMBL2653465 | 0.72 | ESR2 (0.55) | LMNATYRNR1I2ALDH1A1CYP2C9 | |
| SCHEMBL10909749 | 0.72 | ESR1 (0.69) | ESR1ESR2AR | |
| SCHEMBL11221254 | 0.72 | ALDH1A1 (0.53) | LMNATYRNR1I2ALDH1A1CYP2C9 | |
| SCHEMBL30596871 | 0.71 | ESR1 (0.70) | ESR1ESR2AR | |
| SCHEMBL29499858 | 0.71 | ESR1 (0.70) | ESR1ESR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258498-B1 | POLYCARBONATE PROTECTIVE COATING | CANON KABUSHIKI KAISHA (JP) | 2001-07-10 | — | — | US | disclosed |