Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5891966 | 0.92 | PGR (0.36) | PGRPOLBMAPTNR3C1AR | |
| SCHEMBL8410110 | 0.92 | PGR (0.36) | PGRPOLBMAPTNR3C1AR | |
| SCHEMBL8407252 | 0.91 | PGR (0.37) | PGRPOLBMAPTNR3C1AR | |
| SCHEMBL8410127 | 0.90 | PGR (0.47) | PGRPOLBMAPTNR3C1AR | |
| SCHEMBL8407074 | 0.84 | PGR (0.33) | PGRPOLBMAPTNR3C1AR | |
| SCHEMBL8407329 | 0.83 | POLB (0.35) | POLBMAPTAR | |
| SCHEMBL7949847 | 0.81 | POLB (0.34) | POLBMAPTAR | |
| SCHEMBL9178008 | 0.81 | POLB (0.48) | PGRPOLBMAPT | |
| SCHEMBL6864127 | 0.81 | AKR1C3 (0.33) | PGR | |
| SCHEMBL7938353 | 0.80 | POLB (0.34) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |
| EP-0532562-B1 | PROCESS FOR PRODUCING 10$g(b)-H-STEROIDS | SCHERING AG (DE) | 1994-11-23 | — | — | EP | disclosed |