SCHEMBL7950083

SCHEMBL7950083

COC(=O)C(CC(C)C)NC(=O)Cc1c(C)cc(OC)cc1C

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 16/20 0.56
TAS1R1 Q7RTX1 16/20 0.56
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6993810 1.00 TAS1R3 (0.56) TAS1R3TAS1R1CYP3A4HPGD
SCHEMBL6995119 0.89 ALDH1A1 (0.50) TAS1R3TAS1R1
SCHEMBL6995117 0.89 ALDH1A1 (0.50) TAS1R3TAS1R1
SCHEMBL6990895 0.84 TAS1R3 (0.55) TAS1R3TAS1R1
SCHEMBL7959631 0.84 TAS1R3 (0.55) TAS1R3TAS1R1
SCHEMBL7958125 0.84 PTGS2 (0.48) CYP3A4HPGD
SCHEMBL6990078 0.84 PTGS2 (0.48) CYP3A4HPGD
SCHEMBL7964610 0.83 TAS1R3 (0.54) TAS1R3TAS1R1
SCHEMBL6994293 0.83 TAS1R3 (0.54) TAS1R3TAS1R1
SCHEMBL7964617 0.82 TAS1R3 (0.48) TAS1R3TAS1R1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172255-B1 INSECTICIDES; MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-5830826-A Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides BAYER AKTIENGESELLSCHAFT (DE) 1998-11-03 US disclosed