Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990364 | 1.00 | TAS1R3 (0.48) | TAS1R3TAS1R1SMN1; SMN2ALDH1A1THRB | |
| SCHEMBL9594891 | 0.90 | TAS1R3 (0.49) | TAS1R3TAS1R1SMN1; SMN2ALDH1A1THRB | |
| SCHEMBL8744837 | 0.90 | TAS1R3 (0.49) | TAS1R3TAS1R1SMN1; SMN2ALDH1A1THRB | |
| SCHEMBL6996747 | 0.89 | THRA (0.47) | ALDH1A1THRBNPSR1LMNAHTT | |
| SCHEMBL6996743 | 0.89 | THRA (0.47) | ALDH1A1THRBNPSR1LMNAHTT | |
| SCHEMBL7964632 | 0.88 | ALDH1A1 (0.50) | TAS1R3TAS1R1ALDH1A1LMNAHTT | |
| SCHEMBL6994676 | 0.88 | ALDH1A1 (0.50) | TAS1R3TAS1R1ALDH1A1LMNAHTT | |
| SCHEMBL7958125 | 0.85 | PTGS2 (0.48) | ALDH1A1LMNAHTTCYP3A4HPGD | |
| SCHEMBL6990078 | 0.85 | PTGS2 (0.48) | ALDH1A1LMNAHTTCYP3A4HPGD | |
| SCHEMBL7950138 | 0.84 | TAS1R3 (0.44) | TAS1R3TAS1R1SMN1; SMN2ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |