Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959906 | 0.89 | KMT2A (0.39) | KMT2APOLBCYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL7960861 | 0.82 | SHMT1 (0.45) | KMT2APOLBCYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL7959947 | 0.82 | SMN1; SMN2 (0.36) | KMT2ASMN1; SMN2L3MBTL1MEN1TSHR | |
| SCHEMBL7960768 | 0.82 | MEN1 (0.46) | KMT2AHPGDMEN1HTTALDH1A1 | |
| SCHEMBL6992889 | 0.80 | TP53 (0.36) | KMT2APOLBCYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL6994975 | 0.78 | LMNA (0.36) | KMT2APOLBCYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL7960614 | 0.77 | CYP3A4 (0.40) | KMT2APOLBCYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL9593911 | 0.77 | HPGD (0.36) | KMT2AHPGDSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL6475221 | 0.75 | MEN1 (0.44) | KMT2AL3MBTL1MEN1HTTPLA2G2A | |
| SCHEMBL6995163 | 0.74 | AKR1C2 (0.50) | KMT2APOLBCYP3A4HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |