Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992821 | 0.90 | TAS1R3 (0.45) | LMNARXFP1TAS1R3TAS1R1L3MBTL1 | |
| Bicarbonate SCHEMBL9119619 | 0.89 | EPHX2 (0.42) | LMNARXFP1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6987357 | 0.84 | MEN1 (0.42) | TAS1R3TAS1R1KMT2AHPGD | |
| SCHEMBL6997712 | 0.84 | LPAR1 (0.40) | LMNARXFP1TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL7960861 | 0.80 | SHMT1 (0.45) | LMNAL3MBTL1SMN1; SMN2TP53PLA2G2A | |
| SCHEMBL8744778 | 0.80 | TAS1R3 (0.46) | LMNARXFP1TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL4424507 | 0.78 | MEN1 (0.41) | TAS1R3TAS1R1L3MBTL1PLA2G2AKMT2A | |
| SCHEMBL7950147 | 0.78 | KMT2A (0.39) | LMNAL3MBTL1SMN1; SMN2TP53PLA2G2A | |
| SCHEMBL6992889 | 0.77 | TP53 (0.36) | LMNAL3MBTL1SMN1; SMN2TP53PLA2G2A | |
| SCHEMBL4435090 | 0.76 | LPAR1 (0.41) | LMNAL3MBTL1SMN1; SMN2PLA2G2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-B1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |