Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992106 | 0.90 | KMT2A (0.36) | TP53KMT2APOLBCYP3A4HPGD | |
| SCHEMBL7958365 | 0.84 | SMN1; SMN2 (0.37) | KMT2AMAPTTSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL6995171 | 0.84 | MEN1 (0.43) | KMT2AHPGDSHMT1MEN1HTT | |
| SCHEMBL7960861 | 0.82 | SHMT1 (0.45) | TP53KMT2APOLBCYP3A4HPGD | |
| SCHEMBL7950147 | 0.80 | KMT2A (0.39) | TP53KMT2APOLBCYP3A4HPGD | |
| SCHEMBL8744736 | 0.78 | LMNA (0.34) | KMT2APOLBHPGDMAPTTSHR | |
| SCHEMBL6994975 | 0.77 | LMNA (0.36) | TP53KMT2APOLBCYP3A4HPGD | |
| SCHEMBL4421064 | 0.77 | MEN1 (0.42) | KMT2AKDM4EPLA2G2AL3MBTL1MEN1 | |
| SCHEMBL7960614 | 0.76 | CYP3A4 (0.40) | TP53KMT2APOLBCYP3A4HPGD | |
| SCHEMBL4424929 | 0.74 | SMN1; SMN2 (0.41) | KMT2APOLBHPGDPLA2G2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-B1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| WO-1995026954-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |