SCHEMBL7950168

SCHEMBL7950168

Oc1cccc(Oc2ccccc2)c1-c1cnco1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 1/20 0.39
LTA4H P09960 1/20 0.39
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
GAPDH P04406 1/20 0.36
PDK2 Q15119 1/20 0.36
TTR P02766 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAP4K4 O95819 1/20 0.35
PLAU P00749 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
PKM P14618 1/20 0.35
RAB9A P51151 1/20 0.35
IMPDH2 P12268 2/20 0.34
PORCN Q9H237 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7950171 0.76 CYP1A2 (0.39) ALDH1A1
SCHEMBL7964697 0.75 CYP1A2 (0.43) IMPDH2
SCHEMBL27958338 0.73 GAPDH (0.44) LTA4HGAPDHTTRKMT2AKDM4E
SCHEMBL7639737 0.73 GAPDH (0.39) LTA4HGAPDHTTRKMT2AKDM4E
SCHEMBL396882 0.69 ALDH1A1 (0.52) LTA4HTTRKMT2AKDM4EALDH1A1
SCHEMBL29449754 0.68 TTR (0.57) LTA4HTTRKMT2AKDM4EALDH1A1
SCHEMBL260447 0.68 TTR (0.57) LTA4HTTRKMT2AKDM4EALDH1A1
SCHEMBL1903692 0.68 PDK2 (0.48) CYP11B1CYP11B2PDK2MEN1KMT2A
SCHEMBL18189714 0.67 GAPDH (0.45) LTA4HGAPDHTTRKMT2AALDH1A1
SCHEMBL2092322 0.67 GAPDH (0.49) LTA4HGAPDHTTRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268310-B1 CONTROLLING WEEDS NIPPON SODA CO., LTD. (JP) 2001-07-31 US disclosed
US-6107251-A SUCH AS 5-(2-(4,6-DIMETHOXYPYRIMIDINE-2-YLOXY)-6-(4,6-DIMETHOXYTRIAZINE-2 -YLOXY)PHENYL)OXAZOLE AND OTHER COMPOUNDS OF SPECIFIED FORMULA NIPPON SODA CO., LTD. (JP) 2000-08-22 US disclosed
US-5962685-A HERBICIDES NIPPON SODA CO., LTD. (JP) 1999-10-05 US disclosed
EP-0776894-A1 OXAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE NIPPON SODA CO., LTD. (JP) 1997-06-04 EP disclosed