SCHEMBL7639737

SCHEMBL7639737

Oc1cccc(Oc2ccccc2)c1-c1ccccc1.c1ncncn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAPDH P04406 1/20 0.39
TTR P02766 2/20 0.38
CTNNB1 P35222 1/20 0.37
LTA4H P09960 1/20 0.36
NR1H2 P55055 1/20 0.36
BAX Q07812 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27958338 0.92 GAPDH (0.44) GAPDHTTRCTNNB1LTA4HNR1H2
Phosphoric Acid SCHEMBL9017459 0.84 GAPDH (0.42) GAPDHTTRCTNNB1LMNAGAA
SCHEMBL4625341 0.82 HSD17B10 (0.43) GAPDHALDH1A1HPGDESR1ESR2
SCHEMBL6257211 0.81 LMNA (0.45) ALDH1A1NCOA1NCOA3LMNAKMT2A
Pyrophosphoric Acid SCHEMBL28910336 0.80 GAPDH (0.40) GAPDHTTRCTNNB1LMNAGAA
Biphenyl SCHEMBL28813894 0.75 TTR (0.52) TTRCTNNB1LTA4HNR1H2BAX
SCHEMBL28754518 0.73 MEN1 (0.42) ALDH1A1HPGDESR1ESR2LMNA
SCHEMBL28471718 0.73 CAMK2A (0.43) TTRLTA4HNR1H2BAXKMT2A
SCHEMBL7950168 0.73 RHEB (0.39) GAPDHTTRLTA4HALDH1A1LMNA
SCHEMBL396882 0.73 ALDH1A1 (0.52) TTRCTNNB1LTA4HNR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704437-B1 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA SC HOLDING AG (CH) 2002-09-25 EP disclosed
US-5849821-A Tris-aryl-s-triazines substituted with biphenylyl groups CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-12-15 US disclosed
EP-0826675-A1 Tris-aryl s-triazines substituted with biphenylyl groups Ciba SC Holding AG (CH) 1998-03-04 EP disclosed
US-5684070-A FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-11-04 US disclosed
US-5681955-A PHOTOSTABILITY OF POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-10-28 US disclosed
US-5675004-A POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS CIBA-GEIGY CORPORATION (US) 1997-10-07 US disclosed
US-5648488-A Compositions stabilized with red-shifted tris-aryl-s-triazines CIBA-GEIGY CORPORATION (US) 1997-07-15 US disclosed
US-5637706-A ACTINIC RADIATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5556973-A Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY CORPORATION (US) 1996-09-17 US disclosed
US-5543518-A ALKYLATION OF TRIS-ARYL-S-TRIAZINE COMPOUNDS WITH ALKENES, CYCLOALKENES, PHENYLALKENES CIBA-GEIGY CORPORATION (US) 1996-08-06 US disclosed
EP-0704437-A2 Red-shifted tris-aryl-s-triazines and compositions stabilized therewith CIBA-GEIGY AG (CH) 1996-04-03 EP disclosed