SCHEMBL7964697

SCHEMBL7964697

COc1cc(OC)nc(Oc2cccc(Oc3ccccc3)c2-c2cnco2)n1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.43
CYP2C9 P11712 3/20 0.43
CYP2C19 P33261 3/20 0.43
CYP3A4 P08684 2/20 0.43
GAA P10253 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
IMPDH2 P12268 2/20 0.41
ATM Q13315 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7950180 0.89 L3MBTL1 (0.39) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL7950387 0.85 IMPDH2 (0.42) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL7950171 0.85 CYP1A2 (0.39) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL7958560 0.82 IMPDH2 (0.35) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL7950159 0.80 AAK1 (0.40) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL7962465 0.79 NPSR1 (0.45) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL8454604 0.77 LTA4H (0.45) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL7950178 0.76 IMPDH2 (0.32) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL7950168 0.75 RHEB (0.39) IMPDH2
SCHEMBL7950249 0.75 AAK1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268310-B1 CONTROLLING WEEDS NIPPON SODA CO., LTD. (JP) 2001-07-31 US disclosed
US-6107251-A SUCH AS 5-(2-(4,6-DIMETHOXYPYRIMIDINE-2-YLOXY)-6-(4,6-DIMETHOXYTRIAZINE-2 -YLOXY)PHENYL)OXAZOLE AND OTHER COMPOUNDS OF SPECIFIED FORMULA NIPPON SODA CO., LTD. (JP) 2000-08-22 US disclosed