Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720088 | 0.92 | TRPV4 (0.44) | TRPV4KDM4EASPHKDM8NOTUM | |
| SCHEMBL31171409 | 0.92 | TRPV4 (0.44) | TRPV4KDM4EASPHKDM8NOTUM | |
| SCHEMBL8299931 | 0.83 | ALDH1A1 (0.42) | TRPV4KDM4EASPHKDM8KEAP1 | |
| SCHEMBL19554362 | 0.83 | KEAP1 (0.46) | TRPV4KDM4EKEAP1NFE2L2NOTUM | |
| SCHEMBL8304252 | 0.83 | KEAP1 (0.44) | TRPV4KDM4EKEAP1NFE2L2NOTUM | |
| SCHEMBL5495032 | 0.82 | TRPV4 (0.52) | TRPV4 | |
| SCHEMBL8004361 | 0.82 | TRPV4 (0.47) | TRPV4CNR2 | |
| SCHEMBL8299340 | 0.82 | TRPV4 (0.47) | TRPV4KDM4E | |
| SCHEMBL8006776 | 0.82 | TRPV4 (0.47) | TRPV4CNR2 | |
| SCHEMBL1713733 | 0.80 | KDM4E (0.54) | KDM4EASPHKDM8KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054187-A1 | TGR5 ANTAGONISTS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-03-13 | — | — | WO | disclosed |
| EP-0906285-A1 | 3-CYANOARYL PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER AG (DE) | 1999-04-07 | — | — | EP | disclosed |
| EP-0897383-A1 | 3-CYANOARYL PYRAZOLES AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1999-02-24 | — | — | EP | disclosed |
| WO-1997046535-A1 | 3-CYANOARYL PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-11 | — | — | WO | disclosed |
| WO-1997040018-A1 | 3-CYANOARYL PYRAZOLES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-30 | — | — | WO | disclosed |